Centre for Cell Manufacturing Ireland (CCMI) was launched at NUI Galway in 2014 and is the first facility on the island of Ireland to be licensed to manufacture cultured stem cells for human use in clinical trials. CCMI currently manufactures cell therapy products for 4 ongoing clinical trials in Galway and other centres around Europe i.e. VISICORT, Critical Limb Ischemia, NEPHSTROM and ADIPOA2. Human Mesenchymal Stem Cells are being used in these trials as Advanced Therapy Medicinal Products (ATMPs) in the treatment of conditions such as critical limb ischemia (CLI), diabetic kidney disease, transplant rejection and osteoarthritis in the knee. For the first time in Ireland, the Centre for Cell Manufacturing has been established at NUI Galway and licensed to manufacture stem cells for use in human clinical trials. CCMI currently operates on the third floor of the Orbsen Building. It comprises of a 250 Square metre area, within which there are two parallel production suites. Each of the two suites is
capable of clinical grade manufacturing of cellular therapy products. The facility manufactures human adult stem cells (hMSCs) for use in clinical trials, bridging the gap between REMEDI’s research programmes and the clinic. CCMI is accredited under EU
GMP and was granted a manufacturing authorization by the Health Products Regulatory Authority (HPRA) - formerly the Irish Medicines Board (IMB) in 2013 for the manufacture human mesenchymal stem cells, enabling the manufacture of clinical grade Advanced Therapy Medicinal Products (ATMPs) for clinical trials.
 
CCMI GMP facility will also be used for the GMP expansion-production of NK cells, including human umbilical cord derived NK cells. CCMI will work closely with Galway University Hospital and the Clinical Research Facility in sourcing cord blood supplies and
the ultimate translation of cancer cell therapies into clinical trials. This project will allow CCMI the opportunity to develop for the first time manufacturing capacity for NK cell therapy for cancer, which has the potential to deliver transformative cell therapies to patients on academic led clinical trials at a fraction of the cost of current approved cell therapies for cancer.

In addition CCMI conducts training for Scientists and Production personnel in cellular manufacturing and they also organise information seminars and workshops in the cellular manufacturing field.